CCB-TOX is an online continuous contamination bio-monitor that detects chemical and organic toxins and provides real-time alerts, using non-pathogenic luminescent bacteria as living sensors. It continuously draws samples, and when luminescent levels, which indicate toxin levels, drastically decrease relative to the successive online automatic tests, an alarm is triggered within 5 to 15 minutes. CCB-TOX minimizes false alarms and is easy to use: no calibration is needed and monthly reagent refill cartridges are easy to replace.